(Reuters) – The next is a roundup of among the newest scientific research on the novel coronavirus and efforts to search out therapies and vaccines for COVID-19, the sickness brought on by the virus.
Coronavirus can harm the mind with out infecting it
The brand new coronavirus doesn’t must instantly invade mind tissue to break it, a brand new examine suggests. Researchers examined the brains of 19 sufferers who died from COVID-19, specializing in tissues from areas regarded as extremely vulnerable to the virus: the olfactory bulb, which controls the sense of odor, and the brainstem, which controls respiration and coronary heart price. In 14 sufferers, one or each of those areas contained broken blood vessels – some clotted, and a few leaking. The areas with leakage had been surrounded by irritation from the physique’s immune response, they discovered. However the researchers noticed no indicators of the virus itself, they report in The New England Journal of Medication. “We had been fully stunned,” stated coauthor Dr. Avindra Nath of the Nationwide Institute of Neurological Issues and Stroke in a press release. The harm his staff noticed is normally related to strokes and neuroinflammatory illnesses, he stated. “Thus far, our outcomes counsel that the harm … might not have been brought on by the SARS-CoV-2 virus instantly infecting the mind,” Dr. Nath stated. “Sooner or later, we plan to check how COVID-19 harms the mind’s blood vessels and whether or not that produces among the short- and long-term signs we see in sufferers.” (bit.ly/38jB7K4)
Hair loss surges in NYC minority communities throughout pandemic
Pandemic stress could also be inflicting folks to lose their hair, based on a brand new examine. By mid-summer, charges of a hair-shedding situation referred to as telogen effluvium (TE) had surged greater than 400% in a racially various neighborhood in New York Metropolis, researchers report within the Journal of the American Academy of Dermatology. From November 2019 by way of February 2020, the incidence of TE circumstances was 0.4%. By August, that price had climbed to 2.3%, they discovered. “It’s unclear if the rise in circumstances of TE is extra carefully associated to the physiological toll of an infection or excessive emotional stress,” stated coauthor Dr. Shoshana Marmon of Coney Island Hospital. The rise was due primarily to TE in individuals of shade, significantly within the Hispanic neighborhood, “in step with the disproportionately excessive mortality price of this subset of the inhabitants on account of COVID-19 in NYC,” the authors stated. TE charges rose in smaller non-white minorities as effectively, however not amongst Blacks, who additionally had been severely impacted by COVID-19. Dr. Adam Friedman of George Washington Faculty of Medication and Well being Sciences, who was not concerned within the analysis, stated he too is seeing will increase in TE “and the timing makes loads of sense, because the onset of shedding is often three months following the traumatic occasion,” which might correspond to the rise of the pandemic. (bit.ly/2WRp7sP)
Researchers argue for one vaccine dose to boost provide
A single dose of one of many presently out there COVID-19 vaccines, even when much less efficient than two doses, might have higher inhabitants profit, three analysis teams argued on Tuesday in three papers in Annals of Inside Medication. In massive trials, two-dose regimens of the vaccine from Pfizer Inc and associate BioNTech SE and Moderna Inc’s shot each demonstrated almost 95% efficacy in stopping sickness from the coronavirus. Yale Faculty of Public Well being researchers say a less-effective single-dose may confer higher inhabitants profit than a 95%-effective vaccine requiring two doses. College of Washington researchers say doubling vaccine protection by giving a single dose to extra folks would hasten pandemic management by decreasing transmission charges. Stanford College researchers say delaying second doses in some folks might allow thousands and thousands extra to obtain a vaccine. “In a public well being emergency, a strong argument exists for doing one thing with less-than-perfect outcomes if it will possibly assist extra individuals shortly,” stated Thomas Bollyky of the Council on International Relations in an editorial printed with the papers. “Nevertheless, whether or not various approaches with present vaccines would accomplish this aim is way from clear.” The U.S Meals and Drug Administration stated on Monday the thought of fixing the approved dosing or schedules of COVID-19 vaccines was untimely and never supported by out there information. (bit.ly/2Lp0elG; bit.ly/3hSIyej; bit.ly/3olRBXK; bit.ly/2LsxbgY)
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Reporting by Nancy Lapid and Marilynn Larkin; Modifying by Invoice Berkrot